Ipamorelin

is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. Unlike other GH releasing peptides, ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone.

CAS: 170851-70-4

Molecular Formula:C38H49N9O5

Sequence: XHXFK

Great resources for reading:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108996/

https://www.ncbi.nlm.nih.gov/pubmed/10373343

https://www.ncbi.nlm.nih.gov/pubmed/9849822

https://clinicaltrials.gov/ct2/show/NCT01280344

CJC1295 Without DAC

Also know as, Mod GRF 1-29 is a synthetic analogue of growth hormone-releasing hormone and a growth hormone secretagogue which was developed by ConjuChem Biotechnologies. It is a modified form of GHRH with improved pharmacokinetics, especially in regard to half-life. Wikipedia

Molecular Formula: C152H252N44O42

CAS: 446262-90-4

Sequence: YADAXFXQSYRKVLAQLSARKLLQDXLSR

CJC1295 Without DAC.png

Great resources for reading:

https://academic.oup.com/jcem/article/91/3/799/2843281

https://www.ncbi.nlm.nih.gov/pubmed/16352683

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787983/

https://pubchem.ncbi.nlm.nih.gov/compound/91976842

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