Research
NMN Fact Sheet
| Molecular formula: | C11H15N2O8P |
| Molecular weight: | 334.22 g/mol |
| Purity: | 99%+ |
| Synonyms |
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| Research Applications: |
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NMN (Nicotinamide Mononucleotide) Research
Nicotinamide Mononucleotide (NMN) is a molecule that has been extensively studied for its potential health benefits across various domains. Concerning metabolic health, NMN has shown promise in protecting against diabetes and other metabolic disorders by boosting NAD+ levels, a vital molecule involved in several metabolic reactions.
NMN and Metabolic Health
Research suggests that NMN can contribute to metabolic health by boosting NAD+ levels, a vital molecule involved in several metabolic reactions. This increase in NAD+ levels has been shown to mitigate physiological decline and protect against diseases such as diabetes and diabetic neuropathy [R].
NMN Supports Energy Metabolism
Nicotinamide Mononucleotide (NMN) plays a beneficial role in energy metabolism by acting as a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme central to cellular energy production. NAD+ is involved in various cellular processes, including metabolic pathways, DNA repair, and immune cell activity. However, NAD+ levels decrease with age, leading to a decline in these vital processes and contributing to age-related disorders.
NMN Supports Healthy Aging
NMN and other NAD+ derivatives are thought to be closely related to healthy aging. They can potentially have a prophylactic and therapeutic impact on functional decline, improving age-associated conditions such as neurodegenerative disorders, cardiomyopathy, obesity, and diabetes [R].
NMN and Longevity
NMN has been shown to promote longevity by restoring NAD+ levels, thereby delaying or even reversing several age-related disorders. It has demonstrated therapeutic potential in age-related chronic conditions such as diabetes, cardiovascular issues, and cognitive impairment. NMN also mitigates age-associated physiological changes in various organs, including the liver, adipose tissue, muscle, pancreas, kidney, retina, and central nervous system [R].
NMN Improves Cognitive Function
Cognitive function benefits have also been associated with NMN supplementation. A study on aged mice showed that NMN supplementation rescued neurovascular coupling responses and improved spatial working memory and gait coordination. This suggests that restoring NAD+ concentration may exert beneficial effects on cognitive responses in aging [R].
NMN Helps Manage Chronic Conditions
NMN also shows promise in managing chronic conditions. For instance, it is being studied as a potential treatment for chronic insomnia, with the hypothesis that NMN supplementation could improve sleep quality. Additionally, NMN has been found to inhibit α-amylase and α-glucosidase enzymes, which could lead to a decrease in glucose absorption, offering a potential management strategy for diabetes mellitus [R][R].
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