Product Description

ARA-290 is a synthetic 11-amino acid peptide derived from the non-hematopoietic domain of erythropoietin, designed specifically for laboratory research applications. This molecular compound targets the innate repair receptor pathway to investigate tissue protection mechanisms without stimulating blood cell production.

Research applications include studying inflammatory cytokine inhibition, particularly IL-6 and IL-12, macrophage immune response modulation, and TRPV1 channel interactions related to neuropathic pain and small nerve fiber function.

ARA-290 peptide research explores endothelial regeneration, ischemia protection, and proinflammatory cytokine regulation in controlled laboratory settings. Terms and conditions apply for research use only.

Peptide Specifications

SPECIFICATION	DESCRIPTION
Sequence	ZEQLERALNSS
Molecular Formula	C51H84N16O21
Molecular Weight	1257.3 g/mol
CAS Number	1208243-50-8
PubChem CID	91810664
Synonyms	Cibinetide, PH-BSP, PHBSP, Pyroglutamate HBSP
Purity	≥98.5% (HPLC)
Solubility	Soluble in water and alkaline solutions
Storage Conditions	Store at -4°C, tightly sealed, away from heat and moisture
Physical Appearance	White lyophilized powder
Shelf Life	36 months from date of manufacture when stored properly
Quality Verification	Third-party tested by certified laboratory
Manufacturing Standard	USA-made, pharmaceutical-grade, GMP compliant
Intended Application	In vitro research applications only

Our Product Quality Guarantee

Every Limitless Biotech compound undergoes independent testing for endotoxins and sterility, meeting rigorous research standards through our systematic quality protocols and proactive manufacturing processes.

Buy ARA-290 Peptide From Limitless Biotech

Limitless Biotech provides USA-manufactured ARA-290 for sale with verified molecular sequences and purity through comprehensive third-party testing. We ensure research quality with same-day shipping and dedicated customer support for your scientific endeavors.

Lyophilized Peptides: These peptides are freeze-dried, a process that not only extends shelf life but also preserves the purity and integrity of the peptides during storage.

Non-Lyophilized Peptides: Offered as a dry powder, these peptides, while not as extensively processed as lyophilized peptides, still maintain a high level of purity. Their stability, though not as enhanced as in lyophilized form, is sufficient for maintaining quality under proper storage conditions.

Understanding Our Product Grades

We offer three distinct product grades to support varying research needs. Our Premium Lyophilized line is triple-tested for purity, endotoxins, and sterility, and in most cases includes both double third-party testing and manufacturer HPLC verification. The Standard Lyophilized grade is third-party purity tested and manufacturer verified. Our Standard (Non-Lyophilized) products are also manufacturer verified and third-party purity tested. All products meet a minimum purity of 98.5%, with the vast majority exceeding 99%. Each designation reflects a specific level of quality control and preparation.

Legal Disclaimer

This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.

Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.

The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.

Research

ARA-290 Peptide Structure

Molecular formula:	C₅₁H₈₄N₁₆O₂₁
Molecular weight:	1257.3 g/mol
PubChem CID:	91810664
Synonyms	Cibinetide ARA290 1208243-50-8 PHBSP, PH-BSP
Research Applications:	Tissure Repair Metabolic Control Neuropathic Pain Small Fiber Neuropathy

ARA-290 Research

ARA-290 is a variant of erythropoietin, engineered to selectively interact with the innate repair receptor. This peptide has been shown to decrease inflammatory pathways and promote tissue protection without the hematopoietic effects associated with erythropoietin. Research indicates that ARA-290 can help reduce HbA1c levels, improve cholesterol profiles, modulate neuropathic pain, and stimulate wound repair.

ARA-290 and Tissue Repair

ARA-290’s interaction with the innate repair receptor facilitates tissue protection and repair by antagonizing inflammatory processes. This action has been observed in preclinical models of neuropathy, where ARA-290 reduced allodynia and promoted healing. These properties make it a promising candidate for further research into therapies targeting tissue damage and inflammation [R].

ARA-290 and Metabolic Control

Studies have demonstrated that ARA-290 can improve metabolic control in patients with type 2 diabetes. In a clinical trial, subjects receiving ARA-290 showed significant improvements in hemoglobin A1c (HbA1c) levels and lipid profiles over a 56-day period. These findings suggest that ARA-290 may offer benefits for managing metabolic parameters in diabetic patients [R].

ARA-290 and Neuropathic Pain

ARA-290 has shown promise in alleviating neuropathic pain, particularly in conditions such as sarcoidosis-induced chronic pain. Clinical trials have revealed that ARA-290 provides analgesia greater than placebo without significant safety concerns. This peptide acts on the innate repair receptor, offering a novel approach to pain management in patients with neuropathic conditions [R].

ARA-290 and Small Fiber Neuropathy

Research indicates that ARA-290 can improve symptoms of small fiber neuropathy (SFN) in patients with sarcoidosis. In a randomized, double-blind study, patients treated with ARA-290 experienced significant improvements in pain intensity and quality of life measures compared to those receiving placebo. The peptide also increased corneal nerve fiber density, suggesting its potential as a disease-modifying agent for sarcoidosis-associated SFN [R][R].

COA

Report 99%+ grade

ARA-290 (8mg)